Creamy Chicken and Spinach Casserole

My creamy chicken and spinach casserole is one of those comforting, wholesome dishes I love to make for dinner when I want something hearty yet easy. It’s rich, cheesy, and full of tender chicken, flavorful spinach, and a luscious creamy sauce that ties everything together. I love how it’s a complete meal in one dish—warm, satisfying, and perfect for both busy weeknights and cozy weekends.

Why You’ll Love This Recipe

I love this recipe because it’s incredibly comforting while still feeling balanced. The creamy sauce keeps the chicken moist and flavorful, while the spinach adds a boost of nutrition and freshness. It’s easy to prepare, customizable with different cheeses or seasonings, and bakes beautifully with a golden, bubbly top. Plus, it reheats well, so I can enjoy leftovers the next day.

Ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)

• 2 cups cooked chicken (shredded or diced)

• 3 cups fresh spinach (roughly chopped)

• 1 cup mushrooms (optional, sliced)

• 1 cup shredded mozzarella cheese

• ½ cup grated Parmesan cheese

• 1 cup sour cream or Greek yogurt

• ½ cup cream cheese, softened

• 1 teaspoon garlic powder

• ½ teaspoon onion powder

• Salt and pepper to taste

• ½ cup breadcrumbs (optional, for topping)

• 1 tablespoon olive oil or melted butter (for topping)

Directions

1. I preheat my oven to 375°F (190°C) and lightly grease a medium baking dish.

2. In a large skillet, I sauté the spinach (and mushrooms, if using) until wilted, then remove from heat.

3. In a large bowl, I combine the cooked chicken, sour cream, cream cheese, garlic powder, onion powder, mozzarella, Parmesan, salt, and pepper. I stir until everything is creamy and well mixed.

4. I fold in the sautéed spinach and mix gently until evenly distributed.

5. I spread the mixture evenly into the prepared baking dish.

6. If I’m adding a crunchy topping, I mix breadcrumbs with olive oil or melted butter and sprinkle it evenly over the top.

7. I bake for 25–30 minutes, or until the casserole is bubbly and the top is golden brown.

8. I let it cool for a few minutes before serving—it’s rich, creamy, and delicious straight from the oven.

Servings and Timing

This recipe serves 4 to 6 people and takes about 15 minutes to prepare, plus 30 minutes to bake.

Variations

• Low-Carb Version: I skip the breadcrumbs and just top it with extra cheese for a keto-friendly dish.

• Broccoli Chicken Casserole: I swap spinach for steamed broccoli florets.

• Spicy Twist: I add a pinch of red pepper flakes or a dash of hot sauce for extra heat.

• Cheese Lover’s Casserole: I mix in sharp cheddar or pepper jack for a different cheesy flavor.

• Vegetable Boost: I toss in diced bell peppers, onions, or zucchini for extra color and nutrients.

Storage/Reheating

I store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, I cover the dish with foil and warm it in a 350°F (175°C) oven for about 15 minutes, or microwave individual portions until hot. I don’t freeze it often because the creamy sauce can change texture, but it’s still possible if wrapped tightly and thawed gently before reheating.

FAQs

Can I use rotisserie chicken?

Yes! I often use rotisserie chicken for convenience—it adds extra flavor and saves time.

Can I make this casserole ahead of time?

Absolutely. I prepare the casserole up to the baking step, cover it, and refrigerate for up to 24 hours. I bake it when ready to serve.

Can I use frozen spinach?

Yes, I just make sure to thaw it completely and squeeze out all the excess liquid before mixing it in.

Can I make this casserole lighter?

I use Greek yogurt instead of sour cream and reduced-fat cream cheese and cheese for a lighter but still creamy version.

What can I serve with this casserole?

I like to pair it with a simple green salad, roasted vegetables, or a side of garlic bread.

Conclusion

My creamy chicken and spinach casserole is the ultimate comfort food—rich, flavorful, and satisfying in every bite. I love how it brings together tender chicken, creamy sauce, and melty cheese in one easy, delicious dish. Whether I’m feeding family or just treating myself to something cozy, this casserole always delivers that perfect blend of comfort and flavor.