1. Preheat the oven

Preheat oven to 350°F (175°C).

2. Cook the ground beef

In a large skillet over medium-high heat, cook the ground beef until no longer pink, breaking it apart as it cooks.
Drain excess fat and set aside.

3. Prepare the biscuit base

In a mixing bowl, combine biscuit mix and water until a soft dough forms.
Spray a 9×13-inch casserole dish with cooking spray.
Press the dough evenly into the bottom of the dish.
Bake for 5–8 minutes until lightly set and slightly golden.

4. Cook the vegetables

Add chopped onion and red bell pepper to the cooked beef.
Cook for about 4 minutes until softened.
Stir in taco seasoning and mix well. Remove from heat.

5. Assemble the casserole

Spread the beef mixture evenly over the baked biscuit layer.

6. Prepare the creamy layer

In a bowl, mix sour cream, mayonnaise, green chiles, ¾ cup shredded cheese, and garlic powder until smooth.
Spread evenly over the beef layer.

7. Add salsa and cheese

Spoon small dollops of salsa over the top (no need to spread).
Sprinkle remaining shredded cheese evenly over everything.

8. Bake

Bake uncovered for 30 minutes, or until hot, bubbly, and golden on top.